- 专利标题: T cell epitopes of the hepatitis B virus nucleocapsid protein
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申请号: US106538申请日: 1987-10-07
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公开(公告)号: US4882145A公开(公告)日: 1989-11-21
- 发明人: George B. Thornton , Ann M. Moriarty , David R. Milich , Alan McLachlan
- 申请人: George B. Thornton , Ann M. Moriarty , David R. Milich , Alan McLachlan
- 申请人地址: CA La Jolla
- 专利权人: Scripps Clinic and Research Foundation
- 当前专利权人: Scripps Clinic and Research Foundation
- 当前专利权人地址: CA La Jolla
- 主分类号: C07K14/52
- IPC分类号: C07K14/52 ; A61K39/00 ; A61K39/29 ; C07K7/08 ; C07K14/00 ; C07K14/02 ; C07K14/10 ; C07K14/18 ; C07K14/705 ; C07K19/00 ; C12P21/08
摘要:
Polypeptides corresponding in amino acid residue sequence to T cell stimulating regions of the HBV nucleocapsid protein are disclosed. A method of enhancing the immunogenicity of a polypeptide immunogen comprising operatively linking the polypeptide through an amino acid residue side chain to core protein particles is also disclosed.
公开/授权文献
- USD425059S Digital answering machine 公开/授权日:2000-05-16