发明授权
- 专利标题: Solubilization of hydrophobic materials using lysophospholipid
- 专利标题(中): 使用溶血磷脂溶解疏水材料
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申请号: US821366申请日: 1986-01-22
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公开(公告)号: US4923854A公开(公告)日: 1990-05-08
- 发明人: Colin P. S. Tilcock , Pieter R. Cullis , Michael J. Hope , Andrew S. Janoff
- 申请人: Colin P. S. Tilcock , Pieter R. Cullis , Michael J. Hope , Andrew S. Janoff
- 申请人地址: NJ Princeton
- 专利权人: The Liposome Company, Inc.
- 当前专利权人: The Liposome Company, Inc.
- 当前专利权人地址: NJ Princeton
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/08 ; A61K9/10 ; A61K9/127 ; A61K31/57 ; A61K31/685 ; A61K38/00 ; A61K38/22 ; A61K45/00 ; A61K47/00 ; A61K47/24
摘要:
A method and composition are described for the solubilization of hydrophobic materials using a lysophospholipid. The method includes drying a composition comprising a hydrophobic material-solubilizing effective amount of phospholipid from organic solvent and hydrating the resulting film with an aqueous medium at either a pH of between about 8.5 and about 14.0, or at pH 7.0 followed by reduction of the temperature to less then 0.degree. C.
公开/授权文献
- US5185527A Multispectral superconductive quantum detector 公开/授权日:1993-02-09
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