发明授权
- 专利标题: 17-sulfur-20,21-dinor-eburnamenines
- 专利标题(中): 17-硫-20,21-二氢 - 柏烷宁
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申请号: US415196申请日: 1989-09-29
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公开(公告)号: US4975427A公开(公告)日: 1990-12-04
- 发明人: Francois Clemence , Jean-Luc Haesslein , Claude Oberlander
- 申请人: Francois Clemence , Jean-Luc Haesslein , Claude Oberlander
- 申请人地址: FRX Paris
- 专利权人: Roussel Uclaf
- 当前专利权人: Roussel Uclaf
- 当前专利权人地址: FRX Paris
- 优先权: FRX8813107 19881006
- 主分类号: A61K31/54
- IPC分类号: A61K31/54 ; A61P9/10 ; A61P25/00 ; A61P25/04 ; A61P25/24 ; A61P25/26 ; C07D209/14 ; C07D417/06 ; C07D513/14 ; C07D513/22
摘要:
A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, halogen, alkyl and alkoxy of 1 to 5 carbon atoms, hydroxy, trifluoromethyl and nitro, n is 0,1 or 2 and the group: ##STR2## in all possible racemic or optically active isomer forms and their non-toxic, pharmaceutically acceptable acid addition salts having analgesic, anti-anoxic and anti-ischemic neuronal protective properties.
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