发明授权
- 专利标题: Renin-inhibitory pepstatin phenyl derivatives
- 专利标题(中): 肾素抑制肽抑制肽苯基衍生物
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申请号: US360626申请日: 1989-06-02
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公开(公告)号: US4980283A公开(公告)日: 1990-12-25
- 发明人: Leeyuan Huang , Joseph Dunn, Jr. , Lawrence Koupal , Jerrold Liesch , Otto Hensens , H. Boyd Woodruff
- 申请人: Leeyuan Huang , Joseph Dunn, Jr. , Lawrence Koupal , Jerrold Liesch , Otto Hensens , H. Boyd Woodruff
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07K5/02
- IPC分类号: C07K5/02 ; C12P21/04
摘要:
A phenyl derivative of pepstatin A, which is much more potent than pepstatin in inhibiting renin enzyme activity and has significantly greater selectivity for renin over pepsin inhibition than does pepstatin, which is useful in treating hypertension and congestive heart failure.
公开/授权文献
- US5782583A In-ground barrier 公开/授权日:1998-07-21
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