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US5010002A Human t-PA production using vectors coding DHFR protein 失效
人类t-PA生产使用编码DHFR蛋白的载体

Human t-PA production using vectors coding DHFR protein
摘要:
A method for producing tissue plasminogen activator (t-PA) in eukaryotic host cells is disclosed. Enhanced levels of t-PA production are obtained by co-amplification of the t-PA gene through treatment of cultures transformed with mutant or wild type DHFR with methotrexate.
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