Invention Grant
- Patent Title: Cytorhodin S derivatives and a process for their preparation
- Patent Title (中): Cytorhodin S衍生物及其制备方法
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Application No.: US464695Application Date: 1990-01-18
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Publication No.: US5028698APublication Date: 1991-07-02
- Inventor: Yukiko Tone , Toshiro Iwahashi , Etsuko Ohkouchi , Hiroshi Kitagawa , Isamu Sugawara , Hiroshi Okazaki , Akio Fukuda , Hans G. Berscheid , Hitoko Numata , Junko Usui , Shunji Senda , Akihiko Matsuo , Hiroshi Watanabe , Itsuo Kurobane
- Applicant: Yukiko Tone , Toshiro Iwahashi , Etsuko Ohkouchi , Hiroshi Kitagawa , Isamu Sugawara , Hiroshi Okazaki , Akio Fukuda , Hans G. Berscheid , Hitoko Numata , Junko Usui , Shunji Senda , Akihiko Matsuo , Hiroshi Watanabe , Itsuo Kurobane
- Applicant Address: JPX Tokyo
- Assignee: Hoechst Japan Limited
- Current Assignee: Hoechst Japan Limited
- Current Assignee Address: JPX Tokyo
- Priority: JPX61-147119 19860625; JPX62-74259 19870330
- Main IPC: A61K31/35
- IPC: A61K31/35 ; A61K31/70 ; A61K31/7028 ; A61K31/7034 ; A61K31/704 ; A61K39/395 ; A61P35/00 ; C07D493/14 ; C07H15/252 ; C07K16/30
Abstract:
Cytorhodin S derivatives, especially cytorhodin S-immunoglobulin complexes are disclosed. Cytorhodin S possesses very high anticancer activity, but the complexes act more selectively on cancer cells and are more useful as an anticancer agent. New intermediate derivatives are also useful as an anticancer agent.
Public/Granted literature
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