发明授权
- 专利标题： Cytorhodin S derivatives and a process for their preparation
- 专利标题（中）： Cytorhodin S衍生物及其制备方法
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申请号： US464695申请日： 1990-01-18
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公开(公告)号： US5028698A公开(公告)日： 1991-07-02
- 发明人: Yukiko Tone , Toshiro Iwahashi , Etsuko Ohkouchi , Hiroshi Kitagawa , Isamu Sugawara , Hiroshi Okazaki , Akio Fukuda , Hans G. Berscheid , Hitoko Numata , Junko Usui , Shunji Senda , Akihiko Matsuo , Hiroshi Watanabe , Itsuo Kurobane
- 申请人： Yukiko Tone , Toshiro Iwahashi , Etsuko Ohkouchi , Hiroshi Kitagawa , Isamu Sugawara , Hiroshi Okazaki , Akio Fukuda , Hans G. Berscheid , Hitoko Numata , Junko Usui , Shunji Senda , Akihiko Matsuo , Hiroshi Watanabe , Itsuo Kurobane
- 申请人地址： JPX Tokyo
- 专利权人： Hoechst Japan Limited
- 当前专利权人： Hoechst Japan Limited
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX61-147119 19860625; JPX62-74259 19870330
- 主分类号： A61K31/35
- IPC分类号： A61K31/35 ; A61K31/70 ; A61K31/7028 ; A61K31/7034 ; A61K31/704 ; A61K39/395 ; A61P35/00 ; C07D493/14 ; C07H15/252 ; C07K16/30
摘要：
Cytorhodin S derivatives, especially cytorhodin S-immunoglobulin complexes are disclosed. Cytorhodin S possesses very high anticancer activity, but the complexes act more selectively on cancer cells and are more useful as an anticancer agent. New intermediate derivatives are also useful as an anticancer agent.
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