发明授权
US5041552A Amino acid derivatives with angiotensin II antagonist properties
失效
具有血管紧张素II拮抗剂性质的氨基酸衍生物
- 专利标题： Amino acid derivatives with angiotensin II antagonist properties
- 专利标题（中）： 具有血管紧张素II拮抗剂性质的氨基酸衍生物
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申请号： US529071申请日： 1990-05-25
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公开(公告)号： US5041552A公开(公告)日： 1991-08-20
- 发明人: John C. Hodges , Ila Sircar
- 申请人： John C. Hodges , Ila Sircar
- 申请人地址： NJ Morris Plains
- 专利权人： Warner-Lambert Company
- 当前专利权人： Warner-Lambert Company
- 当前专利权人地址： NJ Morris Plains
- 主分类号： C07D233/68
- IPC分类号： C07D233/68 ; C07D249/08 ; C07D249/12
摘要：
This invention relates to novel amino acid derivatives which antagonize the binding of angiotensin II to its receptors. The compounds are useful in the treatment of hypertension, heart failure, glaucoma, and hyperaldosteronism. Methods of making the compounds, novel intermediates useful in the separation of the compounds, compositions containing the compounds and methods of using them are also covered.
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