Novel fatty amines, amides and salts thereof may be made from the reaction of polyoxyalkylenepolyamine residues with fatty acids and/or fatty acid esters under relatively mild reaction conditions in the absence of a catalyst. Remarkably, the residues or bottoms products from the synthesis of polyoxyalkylenepolyamines, such as triethylene glycol diamine and tetraethylene glycol diamine, also known as JEFFAMINE.RTM. EDR amines, may be reacted with the fatty acids and/or fatty acid esters to give materials useful in corrosion inhibitors, pigment wetting agents, mineral flotation and flocculation aids, asphalt emulsifiers, surfactants, detergents, petroleum additives, etc.