发明授权
- 专利标题： Phospholipase A.sub.2 inhibiting compositions and their use
- 专利标题（中）： 磷脂酶A2抑制组合物及其使用
-
申请号： US260588申请日： 1988-10-21
-
公开(公告)号： US5064817A公开(公告)日： 1991-11-12
- 发明人: Saul Yedgar , Arie Dagan
- 申请人： Saul Yedgar , Arie Dagan
- 申请人地址： ILX Jerusalem
- 专利权人： Yissum Research Development Company of Hebrew University of Jerusalem
- 当前专利权人： Yissum Research Development Company of Hebrew University of Jerusalem
- 当前专利权人地址： ILX Jerusalem
- 优先权： ILX84252 19871023
- 主分类号： C12N9/99
- IPC分类号： C12N9/99 ; A61K31/00 ; A61K31/215 ; A61K31/685 ; A61K31/74 ; A61K47/30 ; A61K47/48 ; A61P7/02 ; A61P29/00 ; A61P43/00 ; C07F9/10 ; C07K14/00 ; C07K14/81 ; C08B31/00 ; C08B37/02 ; C08B37/04
摘要：
Inhibitors of phospholipase A.sub.2 activity at the cell-surface membrane whose molecular structure comprises a cell-permeable PLA.sub.2 -inhibitor moiety covalently bonded directly or indirectly to a physiologically acceptable carrier moiety which is effective to inhibit cell internalization of the cell-permeable PLA.sub.2 -inhibitor moiety, with the proviso that phosphatidylserine is not bonded indirectly via divalent dodecanedioyl to dextrane hydrazide.
公开/授权文献
- US5518455A Quick coupling cue stick 公开/授权日：1996-05-21
信息查询
