发明授权
US5077372A Amine rich fluorinated polyurethaneureas and their use in a method to
immobilize an antithrombogenic agent on a device surface
失效
富胺氟化聚氨酯脲及其在将抗血栓形成剂固定在器械表面上的方法中的用途
- 专利标题： Amine rich fluorinated polyurethaneureas and their use in a method to immobilize an antithrombogenic agent on a device surface
- 专利标题（中）： 富胺氟化聚氨酯脲及其在将抗血栓形成剂固定在器械表面上的方法中的用途
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申请号： US672245申请日： 1991-03-20
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公开(公告)号： US5077372A公开(公告)日： 1991-12-31
- 发明人: Can B. Hu , Donald D. Solomon
- 申请人： Can B. Hu , Donald D. Solomon
- 申请人地址： NJ Franklin Lakes
- 专利权人： Becton, Dickinson and Company
- 当前专利权人： Becton, Dickinson and Company
- 当前专利权人地址： NJ Franklin Lakes
- 主分类号： A61L33/00
- IPC分类号： A61L33/00 ; C08G18/12 ; C08G18/50
摘要：
A thermoplastic polyurethaneurea having free amino groups is the reaction product of a diisocyanate, a fluorinated polyol, a non-fluorinated polyol and a polyamine. The invention includes a shaped polymeric support structure having the thermoplastic polyurethaneurea coated thereon and a medical article comprising the coated support and heparin covalently bonded to the free amino groups of the coated support. In another aspect of the invention, a method for preparing the heparinized medical article is provided.
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