发明授权
- 专利标题: Process for producing optically active amino acids
- 专利标题(中): 生产光活性氨基酸的方法
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申请号: US396694申请日: 1989-08-22
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公开(公告)号: US5081024A公开(公告)日: 1992-01-14
- 发明人: Masao Kuwahara , Michito Tagawa , Takashi Furusato , Hiroyuki Narushima , Shuzo Shinke
- 申请人: Masao Kuwahara , Michito Tagawa , Takashi Furusato , Hiroyuki Narushima , Shuzo Shinke
- 申请人地址: JPX Tokyo
- 专利权人: Nissan Chemical Industries, Ltd.
- 当前专利权人: Nissan Chemical Industries, Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX63-221899 19880905; JPX63-325125 19881223; JPX1-10826 19890119; JPX1-11636 19890120; JPX1-61711 19890314; JPX1-110281 19890428; JPX1-144437 19890607; JPX1-181823 19890714
- 主分类号: C12P13/04
- IPC分类号: C12P13/04 ; C12P41/00
摘要:
An efficient process of optical resolution is provided for producing an L-amino acid represented by the following formula (I): ##STR1## wherein R is --CH.sub.2 CO.sub.2 H, --CH.sub.2 CONH.sub.2, --CO.sub.2 H or ##STR2## in which R.sup.1 is hydrogen atom, an alkyl group having 1 to 10 carbon atoms or a halogen-substituted alkyl group having 1 to 10 carbon atoms. The process comprises an optical resolution of an N-substituted carbonyl-D,L-amino acid represented by the formula (II): ##STR3## (wherein R is the same as defined above and R.sup.2 is an alkanoyl group having 1 to 5 carbon atoms, benzoyl group, a halogen-substituted alkanoyl group having 1 to 5 carbon atoms or a halogen-substituted benzoyl group), its salt or a mixture thereof, by means of cells of a microorganism, a fermentation broth of a microorganism, a treated fermentation broth of a microorganism or a mixture thereof, said microorganism being selected from the bacteria of the genera Serratia, Staphylococcus, Bacillus, Flavobacterium, Achromobacter and Alcaligenes and actinomycetes of the genera Actinoplanes, Streptosporangium and Sebekia.
公开/授权文献
- US5661408A Real-time in-line testing of semiconductor wafers 公开/授权日:1997-08-26