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公开(公告)号：US5081024A
公开(公告)日：1992-01-14
申请号：US396694
申请日：1989-08-22
CPC分类号： C12P41/007 , C12P13/04 , Y10S435/824 , Y10S435/827 , Y10S435/829 , Y10S435/833 , Y10S435/85 , Y10S435/881 , Y10S435/883 , Y10S435/907
摘要： An efficient process of optical resolution is provided for producing an L-amino acid represented by the following formula (I): ##STR1## wherein R is --CH.sub.2 CO.sub.2 H, --CH.sub.2 CONH.sub.2, --CO.sub.2 H or ##STR2## in which R.sup.1 is hydrogen atom, an alkyl group having 1 to 10 carbon atoms or a halogen-substituted alkyl group having 1 to 10 carbon atoms. The process comprises an optical resolution of an N-substituted carbonyl-D,L-amino acid represented by the formula (II): ##STR3## (wherein R is the same as defined above and R.sup.2 is an alkanoyl group having 1 to 5 carbon atoms, benzoyl group, a halogen-substituted alkanoyl group having 1 to 5 carbon atoms or a halogen-substituted benzoyl group), its salt or a mixture thereof, by means of cells of a microorganism, a fermentation broth of a microorganism, a treated fermentation broth of a microorganism or a mixture thereof, said microorganism being selected from the bacteria of the genera Serratia, Staphylococcus, Bacillus, Flavobacterium, Achromobacter and Alcaligenes and actinomycetes of the genera Actinoplanes, Streptosporangium and Sebekia.
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公开(公告)号：US5346919A
公开(公告)日：1994-09-13
申请号：US100171
申请日：1993-08-02
申请人： Tsuneo Watanabe , Takeshi Yasumoto , Michio Murata , Michito Tagawa , Hiroyuki Narushima , Takashi Furusato , Masao Kuwahara , Masami Hanaue , Tatsuya Seki
发明人： Tsuneo Watanabe , Takeshi Yasumoto , Michio Murata , Michito Tagawa , Hiroyuki Narushima , Takashi Furusato , Masao Kuwahara , Masami Hanaue , Tatsuya Seki
IPC分类号： C07D493/04 , C12P17/18 , A61K31/34 , C07D307/93 , C12P7/40
CPC分类号： C07D493/04 , C12P17/181 , C12R1/645
摘要： The present invention relates to the compound A of the formula (A), the related compound B, carboxylic acid derived from acid anhydride group of these compounds and esters and salts thereof, microorganisms for producing the compounds, methods for producing the compounds A and/or B by using the microorganisms, and a treated or untreated fermentation broth obtained by culturing strains belonging to genus Zopfiella or Zopfiella curvata No. 37-3 strain. ##STR1## The present invention provides the compounds A and B, derivatives thereof, and treated or untreated fermentation broth obtained by culturing the strains belonging to genus Zopfiella or Zopfiella curvata No. 37-3 strain, which show an excellent activities as antifungal agent and anti-thrombotic agent.
摘要翻译： 本发明涉及式（A）化合物A，相关化合物B，衍生自这些化合物的酸酐基团的羧酸及其酯和盐，用于制备化合物的微生物，化合物A和/ 或B，以及通过培养属于Zopfiella属或No.37-3菌株的菌株获得的处理或未处理的发酵肉汤。 （A）本发明提供了化合物A和B及其衍生物，以及通过培养属于Zopfiella属或曲霉菌株37-3株的菌株获得的处理或未处理的发酵液，其显示出优异的活性 抗真菌剂和抗血栓形成剂。
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公开(公告)号：US5460814A
公开(公告)日：1995-10-24
申请号：US228712
申请日：1994-04-18
申请人： Tsuneo Watanabe , Takeshi Yasumoto , Michio Murata , Michito Tagawa , Hiroyuki Narushima , Takashi Furusato , Masao Kuwahara , Masami Hanaue , Tatsuya Seki
发明人： Tsuneo Watanabe , Takeshi Yasumoto , Michio Murata , Michito Tagawa , Hiroyuki Narushima , Takashi Furusato , Masao Kuwahara , Masami Hanaue , Tatsuya Seki
IPC分类号： C07D493/04 , C12P17/18 , C12N1/16 , C12P1/02
CPC分类号： C07D493/04 , C12P17/181 , C12R1/645
摘要： The present invention relates to the compound A of the formula (A), the related compound B, carboxylic acid derived from acid anhydride group of these compounds and esters and salts thereof, microorganisms for producing the compounds, methods for producing the compounds A and/or B by using the microorganisms, and a treated or untreated fermentation broth obtained by culturing strains belonging to genus Zopfiella or Zopfiella curvata No. 37-3 strain. ##STR1## The present invention provides the compounds A and B, derivatives thereof, and treated or untreated fermentation broth obtained by culturing the strains belonging to genus Zopfiella or Zopfiella curvata No. 37-3 strain, which show an excellent activities as antifungal agent and anti-thrombotic agent.
摘要翻译： 本发明涉及式（A）化合物A，相关化合物B，衍生自这些化合物的酸酐基团的羧酸及其酯和盐，用于制备化合物的微生物，化合物A和/ 或B，以及通过培养属于Zopfiella属或No.37-3菌株的菌株获得的处理或未处理的发酵肉汤。 （A）本发明提供了化合物A和B及其衍生物，以及通过培养属于Zopfiella属或曲霉菌株37-3株的菌株获得的处理或未处理的发酵液，其显示出优异的活性 抗真菌剂和抗血栓形成剂。
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公开(公告)号：US5266483A
公开(公告)日：1993-11-30
申请号：US911570
申请日：1992-07-09
申请人： Toshihiko Iizuka , Michito Tagawa , Sachiko Yajima , Masao Kuwahara , Hiroshi Haruyama , Toshiyuki Umehara
发明人： Toshihiko Iizuka , Michito Tagawa , Sachiko Yajima , Masao Kuwahara , Hiroshi Haruyama , Toshiyuki Umehara
CPC分类号： C12R1/075 , A01N63/00 , C07K14/325 , Y10S435/832
摘要： The present invention provides novel strains of Bacillus thuringiensis var. Kurstaki, No.145, No.116 and No.161.These strains produce an insecticidal crystal toxin which is useful as an active component in a insect pest-controlling agent.
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5.发明授权Insect controlling agent from strains of Bacillus thuringiensis var. Kurstaki 失效苏云金芽孢杆菌菌株昆虫控制剂 Kurstaki
公开(公告)号：US5516514A
公开(公告)日：1996-05-14
申请号：US110543
申请日：1993-08-23
申请人： Toshihiko Iizuka , Michito Tagawa , Sachiko Yajima , Masao Kuwahara , Hiroshi Haruyama , Toshiyuki Umehara
发明人： Toshihiko Iizuka , Michito Tagawa , Sachiko Yajima , Masao Kuwahara , Hiroshi Haruyama , Toshiyuki Umehara
CPC分类号： C12R1/075 , A01N63/00 , C07K14/325 , Y10S435/832
摘要： A method for protection of a plant from damage caused by an insect pest of the order Lepidoptera and Diptera is disclosed. An insect controlling agent having an active component of an insecticidal crystal toxin produced by Bacillus thuringiensis var. kurstaki No. 145 FERM BP-3905, No. 161 FERM BP-3906, and No. 116 FERM BP-3907 is used in the method for protection of a plant. The insecticidal crystal toxin has a set of molecular weights as determined by 10% SDS-polyacrylamide gel electrophoresis of 125,000 daltons and 60,000 daltons when produced by No. 145, 130,000 daltons and 60,000 daltons when produced by No. 161, and 130,000 daltons and 60,000 daltons when produced by No. 116.
摘要翻译： 公开了一种保护植物免受由鳞翅目和双翅目的虫害引起的损害的方法。 具有由苏云金芽孢杆菌变种产生的杀虫结晶毒素活性成分的昆虫控制剂。 在保护植物的方法中使用Kurstaki No.145FERM BP-3905，No.161FERM BP-3906和116号FERM BP-3907。 杀虫结晶毒素具有一系列分子量，如通过第161号生产第145,130,000道尔顿和60,000道尔顿时产生的125,000道尔顿和60,000道尔顿的10％SDS-聚丙烯酰胺凝胶电泳确定的，并且130,000道尔顿和60,000道尔顿 第116号生产的道尔顿。
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公开(公告)号：US06449555B1
公开(公告)日：2002-09-10
申请号：US09498367
申请日：2000-02-04
申请人： Yoshikazu Ohba , Hideki Ueno , Masao Kuwahara
发明人： Yoshikazu Ohba , Hideki Ueno , Masao Kuwahara
IPC分类号： G08G1123
CPC分类号： G07B15/063 , G08G1/017 , G08G1/20
摘要： This invention is to provide a travel time information arithmetic operation method and apparatus for calculating travel time information using data obtained by a toll collection system. The travel time information arithmetic operation apparatus includes a travel time arithmetic operation section for calculating a travel time (time required by a vehicle to travel from a given point to another given point) of a vehicle on the basis of data obtained by the toll collection system installed on a tollroad and representing the entry point, entry time, exit point, exit time, and model of the vehicle, and date, a tollgate data storage section for storing the data obtained by the toll collection system and travel time data obtained by the travel time arithmetic operation section, and a travel time information arithmetic operation section for calculating an average travel time value using the travel time n-minutes accumulated data stored in the tollgate data storage section and generating travel time information.
摘要翻译： 本发明提供一种使用通过收费系统获得的数据来计算旅行时间信息的旅行时间信息算术运算方法和装置。 行驶时信息算术运算装置包括行驶时间算术运算部，其根据由收费系统获得的数据，计算车辆的行驶时间（车辆从给定点到另一给定点所需的时间） 安装在收费站上，并且代表车辆的入口点，进入时间，出口点，出口时间和型号以及日期，用于存储通过收费系统获得的数据的收费站数据存储部分和由 旅行时间算术运算部，以及行驶时间信息算术运算部，用于使用存储在收费站数据存储部中的行驶时间n分钟累积数据来计算平均行驶时间值，并生成行驶时间信息。
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公开(公告)号：US08306742B2
公开(公告)日：2012-11-06
申请号：US12681726
申请日：2008-07-03
申请人： Aiko Sugawara , Masao Kuwahara , Hiroshi Warita
发明人： Aiko Sugawara , Masao Kuwahara , Hiroshi Warita
CPC分类号： G01C21/26 , G08G1/0104 , G08G1/096816 , G08G1/096844
摘要： A navigation server rapidly generating guide support information in view of a traffic state after occurrence of an accidental situation in a road section, and make a navigation device recognize the same. After occurrence of the accidental situation in a target road section, a changing pattern g2(t) of a cumulative traffic volume CQ of a second position x2 during a first period is estimated, on the basis of a value of a traffic volume Q1 of the target road section at the first time t1. Further, a primary guide support information during the first period is generated on the basis of a standard changing pattern g1(t) of the cumulative traffic volume CQ of the first position x1 and a changing pattern g2(t) of the cumulative traffic volume CQ of the second position x2 as the estimation result.
摘要翻译： 导航服务器在路段中发生意外情况之后，考虑到交通状况，迅速地产生指导支持信息，并使导航装置识别。 在目标路段中发生意外情况之后，基于第一时段中的第二位置x2的累计交通量CQ的变化模式g2（t），基于第 目标路段第一次t1。 此外，基于第一位置x1的累积交通量CQ的标准变化模式g1（t）和累积交通量CQ的变化模式g2（t），生成在第一时段期间的主要指导支持信息 的第二位置x2作为估计结果。
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公开(公告)号：US20100211309A1
公开(公告)日：2010-08-19
申请号：US12681726
申请日：2008-07-03
申请人： Aiko Sugawara , Masao Kuwahara , Hiroshi Warita
发明人： Aiko Sugawara , Masao Kuwahara , Hiroshi Warita
CPC分类号： G01C21/26 , G08G1/0104 , G08G1/096816 , G08G1/096844
摘要： A navigation server rapidly generating guide support information in view of a traffic state after occurrence of an accidental situation in a road section, and make a navigation device recognize the same. After occurrence of the accidental situation in a target road section, a changing pattern g2(t) of a cumulative traffic volume CQ of a second position x2 during a first period is estimated, on the basis of a value of a traffic volume Q1 of the target road section at the first time t1. Further, a primary guide support information during the first period is generated on the basis of a standard changing pattern g1(t) of the cumulative traffic volume CQ of the first position x1 and a changing pattern g2(t) of the cumulative traffic volume CQ of the second position x2 as the estimation result.
摘要翻译： 导航服务器在路段中发生意外情况之后，考虑到交通状况，迅速地产生指导支持信息，并使导航装置识别。 在目标路段中发生意外情况之后，基于第一时段中的第二位置x2的累计交通量CQ的变化模式g2（t），基于第 目标路段第一次t1。 此外，基于第一位置x1的累积交通量CQ的标准变化模式g1（t）和累积交通量CQ的变化模式g2（t），生成在第一时段期间的主要指导支持信息 的第二位置x2作为估计结果。
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