发明授权
- 专利标题： Treatment of human viral infections
- 专利标题（中）： 人类病毒感染的治疗
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申请号： US510590申请日： 1990-04-18
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公开(公告)号： US5086044A公开(公告)日： 1992-02-04
- 发明人: Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
- 申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
- 申请人地址： NC Research Triangle Park
- 专利权人： Burroughs Wellcome Co.
- 当前专利权人： Burroughs Wellcome Co.
- 当前专利权人地址： NC Research Triangle Park
- 主分类号： C07H19/06
- IPC分类号： C07H19/06 ; C07H19/16
摘要：
Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose. Additionally, there is disclosed the treatment of Kaposi's sarcoma with 3'-azido-3'-deoxythymidine (AZT) and the synergistic activity in the treatment of humans infected with HTLV-III of AZT and interferon as well as AZT and acyclovir.
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