Treatment of human viral infections
    6.
    发明授权
    Treatment of human viral infections 失效
    人类病毒感染的治疗

    公开(公告)号:US5086044A

    公开(公告)日:1992-02-04

    申请号:US510590

    申请日:1990-04-18

    IPC分类号: C07H19/06 C07H19/16

    摘要: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose. Additionally, there is disclosed the treatment of Kaposi's sarcoma with 3'-azido-3'-deoxythymidine (AZT) and the synergistic activity in the treatment of humans infected with HTLV-III of AZT and interferon as well as AZT and acyclovir.

    摘要翻译: 使用化合物3'-叠氮基-3'-脱氧胸苷或其药学上可接受的碱性盐来公开用艾滋病病毒携带或感染艾滋病病毒或具有抗艾滋病病毒抗体的艾滋病或人类的治疗。 还公开了3'-叠氮基-3'-脱氧胸苷的5'-单,二和三磷酸或其药学上可接受的碱性盐用于相同目的。 另外,公开了用3'-叠氮基-3'-脱氧胸苷(AZT)处理卡波西氏肉瘤的方法,以及AZT和干扰素以及AZT和阿昔洛韦感染HTLV-III的人的治疗中的协同作用。