发明授权
US5091365A Cyclic peptides as promoters of absorption on administration onto the
mucosa
失效
作为吸收在MUCOSA上的吸收促进剂的循环肽
- 专利标题: Cyclic peptides as promoters of absorption on administration onto the mucosa
- 专利标题(中): 作为吸收在MUCOSA上的吸收促进剂的循环肽
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申请号: US228651申请日: 1988-08-05
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公开(公告)号: US5091365A公开(公告)日: 1992-02-25
- 发明人: Jurgen K. Sandow , Rainer Schmiedel , Klaus Wirth , Hans P. Merkle , Suzanne Raehs
- 申请人: Jurgen K. Sandow , Rainer Schmiedel , Klaus Wirth , Hans P. Merkle , Suzanne Raehs
- 申请人地址: DEX Frankfurt
- 专利权人: Hoechst Aktiengesellschaft
- 当前专利权人: Hoechst Aktiengesellschaft
- 当前专利权人地址: DEX Frankfurt
- 优先权: DEX3726324 19870807
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K47/42 ; A61P43/00
摘要:
The invention relates to the use of aids of the general formula ##STR1## in which B denotes a basic amino acid, A/B denotes an acidic or basic amino acid, X denotes a neutral and hydrophilic amino acid, L denotes a lipophilic neutral amino acid, and R denotes hydrogen or an acyl radical, or the physiologically tolerated salts thereof, for promoting the absorption of peptides and proteins on administration onto the mocosa, as well as to pharmaceutical compositions which contain a pharmacologically effective amount of one or more peptides or proteins as well as an aid of the abovementioned formula.
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