A self-healing tire system containing a tire casing, a tacky sealant material, an inner tube and anti-tack material is described. In one embodiment, either the surface of the inner tube or the inner surface of the tire casing is coated with the tacky sealant material. The surface of the sealant, the opposing surface or both are coated with the anti-tack material. The anti-tack material renders the sealant non-tacky for a sufficient time so that the inner tube can be inserted and inflated. However, the anti-tack material allows the sealant surface to become tacky again thereby adhering to the tube and providing for sealing of the tube when it is punctured. In another embodiment, a release agent is contained between the sealant and the tire casing which facilitates removal of the sealant and tube from the tire casing.