Invention Grant
US5112455A Method for analytically utilizing microfabricated sensors during wet-up
失效
在润湿期间分析利用微波传感器的方法
- Patent Title: Method for analytically utilizing microfabricated sensors during wet-up
- Patent Title (中): 在润湿期间分析利用微波传感器的方法
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Application No.: US555976Application Date: 1990-07-20
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Publication No.: US5112455APublication Date: 1992-05-12
- Inventor: Stephen N. Cozzette , Graham Davis , Lisa A. Holleritter , Imants R. Lauks , Sylvia Piznik , Nicolaas J. Smit , Jody A. Tirinato , Henry J. Wieck , Michael P. Zelin
- Applicant: Stephen N. Cozzette , Graham Davis , Lisa A. Holleritter , Imants R. Lauks , Sylvia Piznik , Nicolaas J. Smit , Jody A. Tirinato , Henry J. Wieck , Michael P. Zelin
- Applicant Address: NJ Princeton
- Assignee: I Stat Corporation
- Current Assignee: I Stat Corporation
- Current Assignee Address: NJ Princeton
- Main IPC: G01N27/26
- IPC: G01N27/26 ; G01N27/27 ; G01N27/327 ; G01N27/414 ; G01N27/416 ; G01N33/543
Abstract:
A method of determining the concentration of a preselected analyte species present in a sample fluid is disclosed, which method comprises: (a) providing an external computational means, a reference electrode and at least one substantially dry-stored sensor capable of exhibiting a response to changes in the concentration of a preselected analyte species before the sensor attains full equilibrated wet-up; (b) establishing electrical contact between the sensor, reference electrode and external computational means; (c) contacting the sensor and reference electrode with a calibrant fluid; (d) performing a first signal measurement in a first time window in the presence of the calibrant fluid; (e) displacing the calibrant fluid after performing the first signal measurement; (f) contacting the sensor and reference electrode with a sample fluid; (g) performing a second signal measurement in a second time window in the presence of the sample fluid; and (h) relating the first and second signal measurements to determine the concentration of the preselected analyte species in the sample fluid before said sensor attains full equilibrated wet-up. Alternative methods are disclosed further for collecting, relating and manipulating the results of the signal measurements to provide useful estimates of the analyte concentrations of interest.
Public/Granted literature
- US5671279A Electronic commerce using a secure courier system Public/Granted day:1997-09-23
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