Invention Grant
US5132319A 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene
biosynthesis
失效
1-（羟基氨基烷基）吲哚衍生物作为白细胞三烯生物合成的抑制剂
- Patent Title: 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene biosynthesis
- Patent Title (中): 1-（羟基氨基烷基）吲哚衍生物作为白细胞三烯生物合成的抑制剂
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Application No.: US676631Application Date: 1991-03-28
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Publication No.: US5132319APublication Date: 1992-07-21
- Inventor: Yves Girard , Pierre Hamel , Daniel Delorme , Rejean Fortin
- Applicant: Yves Girard , Pierre Hamel , Daniel Delorme , Rejean Fortin
- Applicant Address: CAX Kirkland
- Assignee: Merck Frosst Canada, Inc.
- Current Assignee: Merck Frosst Canada, Inc.
- Current Assignee Address: CAX Kirkland
- Main IPC: C07D209/08
- IPC: C07D209/08 ; C07D209/30
Abstract:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
Public/Granted literature
- US5930594A Method of manufacturing rigid floating microstructure elements and a device equipped with such elements Public/Granted day:1999-07-27
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