发明授权
- 专利标题： Recombinant avipox virus and immunological use thereof
- 专利标题（中）： 重组禽病毒及其免疫学应用
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申请号： US537890申请日： 1990-06-14
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公开(公告)号： US5174993A公开(公告)日： 1992-12-29
- 发明人: Enzo Paoletti
- 申请人： Enzo Paoletti
- 申请人地址： NY Albany
- 专利权人： Health Research Inc.
- 当前专利权人： Health Research Inc.
- 当前专利权人地址： NY Albany
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C07K14/02 ; C07K14/035 ; C07K14/11 ; C07K14/125 ; C07K14/145 ; C07K14/15 ; C07K14/165 ; C12N7/01 ; C12N15/863
摘要：
The present invention provides a method for inducing an immunological response in a vertebrate to a pathogen by inoculating the vertebrate with a synthetic recombinant avipox virus modified by the presence, in a non-essential region of the avipox genome, of DNA from any source which codes for and expresses an antigen of the pathogen. The present invention further provides a synthetic recombinant avipox virus modified by the insertion therein of DNA from any source, and particularly from a non-avipox source, into a non-essential region of the avipox genome.
公开/授权文献
- US5811454A 4-amino-fluorobenzamides and their use as cytotoxic prodrugs 公开/授权日：1998-09-22