发明授权
- 专利标题： Anthraquinone derivatives and preparation thereof
- 专利标题（中）： 蒽醌衍生物及其制备方法
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申请号： US543437申请日： 1990-06-26
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公开(公告)号： US5187195A公开(公告)日： 1993-02-16
- 发明人: Nobutaka Oohata , Motoaki Nishikawa , Sumio Kiyoto , Shigehiro Takase , Keiji Hemmi , Hidetsugu Murai , Masakuni Okuhara
- 申请人： Nobutaka Oohata , Motoaki Nishikawa , Sumio Kiyoto , Shigehiro Takase , Keiji Hemmi , Hidetsugu Murai , Masakuni Okuhara
- 申请人地址： JPX Osaka
- 专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： GBX8915110 19890630; GBX8923848 19891023
- 主分类号： C12P13/02
- IPC分类号： C12P13/02 ; A61K31/16 ; A61K31/195 ; A61K31/215 ; A61K38/00 ; A61P9/00 ; A61P9/12 ; A61P11/08 ; A61P13/02 ; A61P15/00 ; C07C323/25 ; C07C323/41 ; C07C323/59 ; C07C323/60 ; C07D209/20 ; C07K5/06 ; C07K5/083 ; C12N1/20 ; C12P13/00 ; C12R1/38 ; C12R1/465
摘要：
Anthraquinone compounds of the formula: ##STR1## wherein: R.sup.1 is hydrogen, hydroxy or acyloxy,R.sup.2 is hydrogen or acyl,R.sup.3 is acyl,R.sup.4 is hydrogen or acyl,R.sup.5 is hydrogen or acyl,R.sup.6 is hydrogen or acyl, andR.sup.7 is hydrogen or acylhave been found to possess endothelin antagonistic properties and are producible by various synthetic and fermentation processes.
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