发明授权
US5215924A Method for the determination of an ion with increased sensitivity, use
of substances which are suitable for this and a corresponding agent
失效
用于确定具有提高灵敏度的离子的方法，使用适用于本发明的物质和相应的试剂
- 专利标题： Method for the determination of an ion with increased sensitivity, use of substances which are suitable for this and a corresponding agent
- 专利标题（中）： 用于确定具有提高灵敏度的离子的方法，使用适用于本发明的物质和相应的试剂
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申请号： US698465申请日： 1991-05-10
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公开(公告)号： US5215924A公开(公告)日： 1993-06-01
- 发明人: Walter Rittersdorf , Werner Guethlein , Detlef Thym , Peter Vogel
- 申请人： Walter Rittersdorf , Werner Guethlein , Detlef Thym , Peter Vogel
- 申请人地址： DEX Mannheim
- 专利权人： Boehringer Mannheim GmbH
- 当前专利权人： Boehringer Mannheim GmbH
- 当前专利权人地址： DEX Mannheim
- 优先权： DEX4015592 19900515
- 主分类号： C07C39/26
- IPC分类号： C07C39/26 ; C07C39/27 ; C07C39/38 ; C07C205/24 ; C07C205/25 ; C07C205/37 ; C07C245/10 ; C07C255/53 ; C07C255/66 ; C07C317/22 ; C07C317/32 ; C07C317/46 ; G01N31/22 ; G01N33/84
摘要：
The invention relates to a method for determining an ion in an aqueous sample. The method involves contacting the sample with a water immiscible material including an ionophore, a pH indicator and a compound which stabilizes sensitivity of the assay. The ion reacts with the ionophore in the water immiscible material, releasing a proton which reacts with the pH indicator generating a color change which is representative of the ion to be measured. The stabilizing compound stabilizes this change. Also described are compositions including the three recited elements, and various new compounds useful as the stabilizer.
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