发明授权
US5238955A Ethylene-substituted phenylalkylethylenediamine-platinum (II or IV)
derivatives and phenylalkylethylenediamines
失效
乙烯取代的苯基烷基乙二胺 - 铂(II或IV)衍生物和苯基烷基亚乙基二胺
- 专利标题: Ethylene-substituted phenylalkylethylenediamine-platinum (II or IV) derivatives and phenylalkylethylenediamines
- 专利标题(中): 乙烯取代的苯基烷基乙二胺 - 铂(II或IV)衍生物和苯基烷基亚乙基二胺
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申请号: US981475申请日: 1992-11-25
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公开(公告)号: US5238955A公开(公告)日: 1993-08-24
- 发明人: Henri Brunner , Peter Hankofer , Friedrich Maiterth , Jurgen Engel , Wolfgang Schumacher , Peter Hilgard , Rainer Voegeli
- 申请人: Henri Brunner , Peter Hankofer , Friedrich Maiterth , Jurgen Engel , Wolfgang Schumacher , Peter Hilgard , Rainer Voegeli
- 申请人地址: DEX
- 专利权人: Asta Pharma AG
- 当前专利权人: Asta Pharma AG
- 当前专利权人地址: DEX
- 优先权: DEX4011520 19900410
- 主分类号: C07C211/27
- IPC分类号: C07C211/27 ; C07C211/28 ; C07C211/41 ; C07C211/42 ; C07C215/52 ; C07C217/60 ; C07C217/62 ; C07D217/14 ; C07D311/68 ; C07F15/00 ; C08B37/00
摘要:
Antitumor acting platinum(II or IV) complexes of the general formula ##STR1## where B represents a phenyl-C.sub.1 -C.sub.4 -alkyl radical which is optionally substituted in the phenyl nucleus by the radical R.sub.1 and R.sub.1 is hydrogen, halogen, trihalogen methyl, C.sub.1 -C.sub.6 -alkyl, hydroxy, C.sub.1 -C.sub.6 -alkoxy or C.sub.2 -C.sub.6 -alkanoyloxy or where B together with the structural part H.sub.2 N-CR.sub.2
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