发明授权
- 专利标题： Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it
- 专利标题（中）： 水溶性碱金属磺酸盐取代的二萘基膦过渡金属络合物及其对映选择性氢化法
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申请号： US977638申请日： 1992-11-17
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公开(公告)号： US5274146A公开(公告)日： 1993-12-28
- 发明人: Takerou Ishizaki , Hidenori Kumobayashi
- 申请人： Takerou Ishizaki , Hidenori Kumobayashi
- 申请人地址： JPX Tokyo
- 专利权人： Takasago International Corporation
- 当前专利权人： Takasago International Corporation
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX3-331535 19911121
- 主分类号： B01J31/22
- IPC分类号： B01J31/22 ; B01J31/24 ; C07B61/00 ; C07C211/27 ; C07C213/00 ; C07C215/20 ; C07C215/28 ; C07F9/50 ; C07F15/00 ; C07F9/02
摘要：
An alkali metal sulfonate-substituted binaphthyl-phosphine transition metal complex is disclosed, which is represented by formula (I)[M(X).sub.n (Q)(SO.sub.3 A-BINAP)]Y (I)whereinM represents a transition metal atom;SO.sub.3 A-BINAP represents a tertiary phosphine represented by formula (II) ##STR1## in which A represents an alkali metal atom; X represents a chlorine atom, a bromine atom, or an iodine atom;when n is 1, M represents ruthenium, Q represents benzene or p-cymene, and Y represents a chlorine atom, a bromine atom, or an iodine atom;when n is 0 and M is iridium or rhodium, Q represents 1,5-cyclo-octadiene or norbornadiene, and Y represents ClO.sub.4, PF.sub.6 or BF.sub.4 ; andwhen n is 0 and M is palladium, Q represents .pi.-allyl, and Y represents ClO.sub.4, PF.sub.6, or BF.sub.4. A method of enantioselectively hydrogenating an olefin, a ketone, or an imine, which comprises carrying out the enantioselective hydrogenation using as a catalyst the alkali metal sulfonate-substituted binaphthylphosphine transition metal complex represented by formula (I) is also disclosed.