发明授权
- 专利标题: Benzofuran derivatives
- 专利标题(中): 苯并呋喃衍生物
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申请号: US883164申请日: 1992-05-15
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公开(公告)号: US5310927A公开(公告)日: 1994-05-10
- 发明人: Barry C. Ross , David Middlemiss , David I. C. Scopes , Torquil I. M. Jack , Kevin S. Cardwell , Michael D. Dowle , Duncan B. Judd
- 申请人: Barry C. Ross , David Middlemiss , David I. C. Scopes , Torquil I. M. Jack , Kevin S. Cardwell , Michael D. Dowle , Duncan B. Judd
- 申请人地址: GB2 London
- 专利权人: Glaxo Group Limited
- 当前专利权人: Glaxo Group Limited
- 当前专利权人地址: GB2 London
- 优先权: GBX9110625.2 19910516
- 主分类号: A61K31/415
- IPC分类号: A61K31/415 ; A61K31/665 ; A61P9/00 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P11/00 ; A61P25/18 ; A61P25/20 ; A61P25/24 ; A61P25/26 ; A61P25/28 ; A61P25/30 ; A61P43/00 ; C07D307/82 ; C07D405/06 ; C07D405/14 ; C07F9/655 ; C07D407/12 ; A61K31/41 ; C07D
摘要:
The invention provides compounds of formula (I): ##STR1## or a physiologically acceptable salt, solvate or metabolically labile ester thereof whereinR.sup.1 represents a hydrogen atom or a halogen atom or a group selected from C.sub.1-6 alkyl, C.sub.2-6 alkenyl, fluoroC.sub.1-6 alkyl, C.sub.1-6 alkoxy, --CHO, --CO.sub.2 H or --COR.sup.2 ;Ar represents the group ##STR2## Het represents an N-linked imidazolyl group optionally substituted by one, two or three substituents.The compounds may be used in the treatment or prophylaxis of hypertension and diseases associated with cognitive disorders.
公开/授权文献
- US6111163A Elastomeric film and method for making the same 公开/授权日:2000-08-29
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