发明授权
- 专利标题: Substituted pyrimidines, pyrimidinones and pyridopyrimidines
- 专利标题(中): 取代的嘧啶,嘧啶酮和吡啶并嘧啶
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申请号: US908143申请日: 1992-07-31
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公开(公告)号: US5324729A公开(公告)日: 1994-06-28
- 发明人: Eric E. Allen , William J. Greenlee , Malcolm MacCoss , Arthur A. Patchett
- 申请人: Eric E. Allen , William J. Greenlee , Malcolm MacCoss , Arthur A. Patchett
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07D239/26
- IPC分类号: C07D239/26 ; C07D239/28 ; C07D239/36 ; C07D239/38 ; C07D239/42 ; C07D403/10 ; C07D471/04 ; C07F9/6512 ; A61K31/505
摘要:
Substituted pyrimidines, pyrimidinones and pyridopyrimidines of formula (I) are as angiotensin II antagonists useful in the treatment of hypertension, ocular hypertension and certain CNS ailments: ##STR1## wherein K is --N(R.sup.8a)--C(.dbd.M) or --N.dbd.C(R.sup.8b) where M is O or NR.sup.22.
公开/授权文献
- US5822565A Method and apparatus for configuring a computer system 公开/授权日:1998-10-13
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