发明授权
US5324742A Aldose reductase inhibitor obtained from Crucibulum sp. RF-3817
失效
从Crucibulum sp。获得的醛糖还原酶抑制剂 RF-3817
- 专利标题： Aldose reductase inhibitor obtained from Crucibulum sp. RF-3817
- 专利标题（中）： 从Crucibulum sp。获得的醛糖还原酶抑制剂 RF-3817
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申请号： US697009申请日： 1991-05-08
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公开(公告)号： US5324742A公开(公告)日： 1994-06-28
- 发明人: Tadashi Yoshida , Toshiyuki Kato , Yoshimi Kawamura , Koichi Matsumoto , Hiroshi Itazaki
- 申请人： Tadashi Yoshida , Toshiyuki Kato , Yoshimi Kawamura , Koichi Matsumoto , Hiroshi Itazaki
- 申请人地址： JPX Osaka
- 专利权人： Shionogi & Co., Ltd.
- 当前专利权人： Shionogi & Co., Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： JPX2-142463 19900530
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61P3/08 ; A61P3/10 ; A61P27/02 ; A61P27/12 ; A61P43/00 ; C07D491/04 ; C07D491/048 ; C12N9/99 ; C12P17/18 ; C12Q1/26 ; C12R1/645
摘要：
The present invention relates to a novel aldose reductase inhibitor of the formula: ##STR1## wherein X is methylene or carbonyl;R is ##STR2## R.sup.1, R.sup.2, R.sup.3, and R.sup.4 each is hydrogen or lower alkyl, to a method for producing the inhibitor by culturing Crucibulum sp. RF-3817 or its variants, and to an agent for inhibiting an aldose reductase comprising the inhibitor.
公开/授权文献
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