发明授权
US5329035A Process for producing 2,3-disubstituted-4-substituted cyclopentanones, enantiomorphs, or mixtures thereof 失效
2,3-二取代-4-取代的环戊酮,对映体或其混合物的制备方法

Process for producing 2,3-disubstituted-4-substituted cyclopentanones,
enantiomorphs, or mixtures thereof
摘要:
A process for producing a 2,3-disubstituted-4-substituted cyclopentanone, an enantiomorph thereof, or a mixture of these in an arbitrary ratio.The process comprises (A) subjecting a 4-substituted-2-cyclopentenone, an enantiomorph thereof, or a mixture of these in an arbitrary ratio, and an organocopper compound to conjugate addition-reaction, and thereafter (B) reacting the resulting enolate intermediate with a halide in the presence of a phenyl organotin compound.
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