发明授权
- 专利标题: New use of the adenosine antagonist
- 专利标题(中): 新使用的腺苷拮抗剂
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申请号: US847286申请日: 1992-03-10
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公开(公告)号: US5338743A公开(公告)日: 1994-08-16
- 发明人: Youichi Shiokawa , Atsushi Akahane , Hirohito Katayama , Takafumi Mitsunaga
- 申请人: Youichi Shiokawa , Atsushi Akahane , Hirohito Katayama , Takafumi Mitsunaga
- 申请人地址: JPX Osaka
- 专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: PHX42760 19910709
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/445 ; A61K31/495 ; A61K31/50 ; A61K31/505 ; A61K31/52 ; A61K31/535 ; A61K31/55 ; C07D471/04 ; C07D473/02 ; A61K31/33 ; A61K31/395 ; A61K31/435 ; A61K31/53 ; A61K31/54
摘要:
The present method for the treatment of pancreatitis, which comprises administering an effective amount of a pyrazolopyridine compound of the following formula: ##STR1## wherein R.sup.1 is lower alkyl, (substituted) aryl, or a heterocyclic group,R.sup.2 is a group of the formula ##STR2## wherein R.sup.4 is protected amino or hydroxy and R.sup.5 is hydrogen or lower alkyl; cyano; a group of the formula --A--R.sup.6, wherein R.sup.6 is an acyl group, and A is (halogenated) lower aliphatic hydrocarbon group; amidated carboxy; an unsaturated heterocyclic group; or (protected) amino; andR.sup.3 is hydrogen, lower alkyl, lower alkoxy or halogen; or a pharmaceutically acceptable salt thereof, to a human being having pancreatitis or an animal having pancreatitis in need thereof.
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