发明授权
US5340820A Cycloaminoalkoxyphenyl derivatives, a process for their preparation as
well as the compositions containing them
失效
环氨基烷氧基苯基衍生物,其制备方法以及含有它们的组合物
- 专利标题: Cycloaminoalkoxyphenyl derivatives, a process for their preparation as well as the compositions containing them
- 专利标题(中): 环氨基烷氧基苯基衍生物,其制备方法以及含有它们的组合物
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申请号: US844979申请日: 1992-03-02
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公开(公告)号: US5340820A公开(公告)日: 1994-08-23
- 发明人: Jean Gubin , Pierre Chatelain , Jean Lucchetti
- 申请人: Jean Gubin , Pierre Chatelain , Jean Lucchetti
- 申请人地址: FRX Paris
- 专利权人: Elf Sanofi
- 当前专利权人: Elf Sanofi
- 当前专利权人地址: FRX Paris
- 优先权: FRX8901555 19890207
- 主分类号: C07D209/08
- IPC分类号: C07D209/08 ; A61K31/34 ; A61K31/343 ; A61K31/38 ; A61K31/40 ; A61K31/403 ; A61K31/404 ; A61K31/415 ; A61K31/42 ; A61K31/421 ; A61K31/47 ; A61K31/472 ; A61P9/00 ; A61P27/02 ; C07D209/30 ; C07D217/04 ; C07D231/12 ; C07D231/18 ; C07D263/46 ; C07D307/79 ; C07D307/82 ; C07D333/62 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D471/04 ; C07D215/20 ; A61K31/44
摘要:
Cycloaminoalkoxyphenyl derivatives useful for the treatment of certain pathological syndromes of the cardiovascular system and ocular diseases of formula: in which:B represents a --S--, --SO-- or --SO.sub.2 -- group,R.sub.1 and R.sub.2, which are identical or different, each denotes hydrogen, a methyl or ethyl radical or a halogen such as chlorine, bromine or iodine,A denotes a straight or linear alkylene radical, having from 2 to 5 carbon atoms or a 2-hydroxypropylene radical in which the hydroxy is optionally substituted by a lower alkyl radical,Am denotes a group: ##STR1## in which: R.sub.3, R'.sub.3 and R".sub.3, which are identical or different, each denotes hydrogen, a halogen atom such as chlorine or bromine, a lower alkyl group or a lower alkoxy group, R.sub.4 denotes hydrogen or an alkyl radical,n and m, identical or different, each denotes 0, 1, 2 or 3,Cy represents a group of formula: ##STR2## pharmaceutically acceptable salts thereof.
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