发明授权
US5358718A Tablet containing mesna as active substance and method of making same
失效
片剂含有mesna作为活性物质及其制备方法
- 专利标题： Tablet containing mesna as active substance and method of making same
- 专利标题（中）： 片剂含有mesna作为活性物质及其制备方法
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申请号： US96422申请日： 1993-07-26
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公开(公告)号： US5358718A公开(公告)日： 1994-10-25
- 发明人: Dieter Sauerbier , Jurgen Engel , Eckhard Milsmann
- 申请人： Dieter Sauerbier , Jurgen Engel , Eckhard Milsmann
- 申请人地址： DEX Hanau
- 专利权人： Degussa
- 当前专利权人： Degussa
- 当前专利权人地址： DEX Hanau
- 优先权： DEX4022525 19900716
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K9/20 ; A61K9/46 ; A61K9/50 ; A61K31/185 ; A61K47/00
摘要：
A granulate containing mesna is made by granulating mesna in the presence of an alcohol, acetone or a mixture of one of these with water. The granulate may be converted to tablets, along with other agents. The tablets contain:0.01-1 parts by weight of a binding agent0.03-0.4 parts by weight of a disintegrant0.01-0.2 parts by weight of a lubricant and0.1-1 parts by weight of a filling agent as well as, in the case of an effervescent tablet, an additional 0.05-30 parts by weight of a conventional physiologically acceptable effervescent mixture.
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