发明授权
US5364944A Substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid
compounds
失效
取代苯甲酰基苯，联苯基和2-恶唑烷酸化合物
- 专利标题： Substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid compounds
- 专利标题（中）： 取代苯甲酰基苯，联苯基和2-恶唑烷酸化合物
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申请号： US001141申请日： 1993-01-06
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公开(公告)号： US5364944A公开(公告)日： 1994-11-15
- 发明人: Amedeo A. Failli , Anthony F. Kreft, III , John H. Musser , Annette L. Banker , James A. Nelson , Uresh S. Shah , Dennis M. Kubrak
- 申请人： Amedeo A. Failli , Anthony F. Kreft, III , John H. Musser , Annette L. Banker , James A. Nelson , Uresh S. Shah , Dennis M. Kubrak
- 申请人地址： NJ Madison
- 专利权人： American Home Products Corporation
- 当前专利权人： American Home Products Corporation
- 当前专利权人地址： NJ Madison
- 主分类号： C07C45/00
- IPC分类号： C07C45/00 ; C07C45/63 ; C07C45/72 ; C07C59/90 ; C07C69/738 ; C07C205/45 ; C07C255/40 ; C07D215/14 ; C07D263/32 ; C07D277/24 ; C07D413/12 ; C07D233/54
摘要：
There are disclosed substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid derivatives and the pharmacologically acceptable salts thereof as inhibitors of PLA.sub.2 and lipoxygenase, and their use in the treatment of inflammatory conditions, such as rheumatoid arthritis, ulcerative colitis, psoriasis and other immediate hypersensitivity reactions; in the treatment of leukotriene-mediated naso-bronchial obstructive air-passageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like; and as gastric cytoprotective agents.
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