发明授权
- 专利标题: Albumin preparation and method for preserving the same
- 专利标题(中): 白蛋白制剂及其保存方法
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申请号: US66157申请日: 1993-05-28
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公开(公告)号: US5372997A公开(公告)日: 1994-12-13
- 发明人: Masahiro Inoue , Hirokazu Ito , Shinji Tomioka , Sadao Yabushita , Koei Ikariya , Kohichi Furuta
- 申请人: Masahiro Inoue , Hirokazu Ito , Shinji Tomioka , Sadao Yabushita , Koei Ikariya , Kohichi Furuta
- 申请人地址: JPX Osaka
- 专利权人: The Green Cross Corporation
- 当前专利权人: The Green Cross Corporation
- 当前专利权人地址: JPX Osaka
- 优先权: JPX2-339949 19901130
- 主分类号: A61K38/16
- IPC分类号: A61K38/16 ; A61J1/05 ; C07K14/435 ; C07K14/76 ; C07K14/765 ; A61K37/00 ; B65D23/00
摘要:
It has been found that aluminum, which is considered as to cause various diseases such as dialysis dementia, bone diseases, hypochromic anemia and Alzheimer's disease, would be eluted into a conventional albumin preparation preserved in a hard glass container, which increases the aluminum concentration of the preparation. According to the present invention, it has been found that the substitution of the conventional hard glass container with a soft glass container dealkalized by, for example, treatment with sulfurous acid gas or ammonium sulfate solution for preserving an albumin preparation can make it possible to prevent the elution of aluminum from the container, thus giving a highly safe albumin preparation which can be maintained with an extremely low aluminum concentration over a long period of time.
公开/授权文献
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