发明授权
- 专利标题： Active fragments of fibroblast growth factor
- 专利标题（中）： 成纤维细胞生长因子的活性片段
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申请号： US054650申请日： 1993-04-26
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公开(公告)号： US5387673A公开(公告)日： 1995-02-07
- 发明人: Andrew P. Seddon , Peter Bohlen
- 申请人： Andrew P. Seddon , Peter Bohlen
- 申请人地址： NJ Wayne
- 专利权人： American Cyanamid Company
- 当前专利权人： American Cyanamid Company
- 当前专利权人地址： NJ Wayne
- 主分类号： C07K7/00
- IPC分类号： C07K7/00 ; A61K38/00 ; C07K14/50 ; C12N15/09 ; C12N15/12 ; C12P21/02 ; C12R1/19 ; C12N15/00 ; C07H7/00 ; C07H13/00
摘要：
The present invention relates to novel fragments of basic fibroblast growth factor (bFGF). The mitogenic potency of one of these bFGF fragments, identified as HBF-2 is about 25-50 fold less than that of native bFGF but at least 10.sup.3 -10.sup.4 fold more active than that of previously reported synthetic fragments of bFGF. Therefore, the present invention provides the shortest fragment of bFGF that retains substantial biologic activity.
公开/授权文献
- USD384278S Die-cut blank for combined display card and easel 公开/授权日：1997-09-30
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