发明授权
US5389661A Imidazole and 1,2,4-triazole derivatives with angiotensin II antagonist
properties
失效
咪唑和1,2,4-三唑衍生物与血管紧张素II拮抗剂的性质
- 专利标题: Imidazole and 1,2,4-triazole derivatives with angiotensin II antagonist properties
- 专利标题(中): 咪唑和1,2,4-三唑衍生物与血管紧张素II拮抗剂的性质
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申请号: US194535申请日: 1994-02-10
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公开(公告)号: US5389661A公开(公告)日: 1995-02-14
- 发明人: Ila Sircar , Jagadish C. Sircar
- 申请人: Ila Sircar , Jagadish C. Sircar
- 申请人地址: NJ Morris Plains
- 专利权人: Warner-Lambert Company
- 当前专利权人: Warner-Lambert Company
- 当前专利权人地址: NJ Morris Plains
- 主分类号: C07D401/06
- IPC分类号: C07D401/06 ; C07D403/06 ; C07D403/14 ; A61K31/41 ; A61K31/415 ; C07D257/04
摘要:
This invention relates to novel substituted imidazole and triazole derivatives which antagonize the binding of angiotensin II to its receptors. The compounds are useful in the treatment of hypertension, heart failure, glaucoma, and hyperaldosteronism. Methods of making the compounds, novel intermediates useful in the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of using them are also covered.
公开/授权文献
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