发明授权
- 专利标题: Mutants of bone morphogenetic proteins
- 专利标题(中): 骨形态发生蛋白的突变体
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申请号: US163877申请日: 1993-12-07
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公开(公告)号: US5399677A公开(公告)日: 1995-03-21
- 发明人: Neil M. Wolfman , John McCoy
- 申请人: Neil M. Wolfman , John McCoy
- 申请人地址: MA Cambridge
- 专利权人: Genetics Institute, Inc.
- 当前专利权人: Genetics Institute, Inc.
- 当前专利权人地址: MA Cambridge
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; C07K14/51 ; C12N15/12 ; C12P21/02 ; C12R1/19 ; C12N15/18 ; A61K37/36
摘要:
DNA molecules encoding mutant forms of bone morphogenetic proteins (BMP) are disclosed, The mutant forms of BMP can be produced bacterially and refolded to produce biologically active homodimers or heterodimers of BMP. A method of making such mutant BMPs is also disclosed.
公开/授权文献
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