发明授权
- 专利标题: 23-oxa-derivatives in the vitamin D series, process for their production, pharmaceutical preparations containing these derivatives as well as their use pharmaceutical agents
- 专利标题(中): 维生素D系列中的23-氧杂衍生物,其制备方法,含有这些衍生物的药物制剂及其用途药剂
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申请号: US90201申请日: 1993-07-19
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公开(公告)号: US5411949A公开(公告)日: 1995-05-02
- 发明人: Gunter Neef , Andreas Steinmeyer , Gerald Kirsch , Katica Schwarz , Martin Haberey , Ruth Thieroff-Ekerdt , Petra Rach
- 申请人: Gunter Neef , Andreas Steinmeyer , Gerald Kirsch , Katica Schwarz , Martin Haberey , Ruth Thieroff-Ekerdt , Petra Rach
- 申请人地址: DEX Berlin and Bergkamen
- 专利权人: Schering Aktiengesellschaft
- 当前专利权人: Schering Aktiengesellschaft
- 当前专利权人地址: DEX Berlin and Bergkamen
- 优先权: DEX4101953.9 19910119
- 主分类号: A61K31/59
- IPC分类号: A61K31/59 ; A61P17/00 ; A61P35/00 ; C07C401/00
摘要:
23-Oxa-derivatives in the vitamin D series of formula I ##STR1## are described in which R.sup.1, R.sup.2 and R.sup.4 independently of one another mean a hydrogen atom or an acyl group with 1 to 9 carbon atoms,R.sup.3 each means a hydrogen atom or each a linear or branched alkyl group with 1 to 4 carbon atoms and X means an alkylene radical--(CH.sub.2).sub.n -- with n=1, 2, 3, and if n=1, R.sup.3 each cannot be a methyl or propyl group, as well as a process for their production.The compounds have proliferation-inhibiting and cell-differentiation effects and are suitable for the production of pharmaceutical agents.
公开/授权文献
- US6151738A Bad extension backrest chest 公开/授权日:2000-11-28
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