发明授权
- 专利标题: Water soluble high molecular weight polymerized drug preparation
- 专利标题(中): 水溶性高分子量聚合药物制剂
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申请号: US496741申请日: 1990-03-21
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公开(公告)号: US5412072A公开(公告)日: 1995-05-02
- 发明人: Yasuhisa Sakurai , Teruo Okano , Kazunori Kataoka , Noriko Yamada , Shohei Inoue , Masayuki Yokoyama
- 申请人: Yasuhisa Sakurai , Teruo Okano , Kazunori Kataoka , Noriko Yamada , Shohei Inoue , Masayuki Yokoyama
- 申请人地址: JPX Tokyo
- 专利权人: Research Development Corp. of Japan
- 当前专利权人: Research Development Corp. of Japan
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX1-116082 19890511
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; A61K9/00 ; A61K31/785 ; A61K47/42 ; A61K47/48 ; A61P35/00 ; C08G69/10 ; C08G69/40 ; C08G69/48 ; C07K9/00
摘要:
This invention is a water-soluble high molecular polymerized drug comprising a water-soluble clock copolymer having a hydrophilic segment and a hydrophobic pharmacological-functioning segment to side chain of which a drug is bonded. The hydrophilic first segments of the present invention include polyethylene glycol, polysaccharides, polyacrylamide, and so on. The hydrophobic segments being attached to a drug include polyaspartic acid, polyglutamic acid, polylysine, or derivatives thereof. Drugs to be attached to the hydrophobic segment include anti-cancer drugs, drugs for central nerve, drugs for circulatory organs, and so on.
公开/授权文献
- US5563499A Reducing current supplied to an integrated circuit 公开/授权日:1996-10-08
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