发明授权
- 专利标题： Therapeutic uses of bactericidal/permeability-increasing protein dimer products
- 专利标题（中）： 杀菌/增加蛋白质二聚体产品的治疗用途
-
申请号： US212132申请日： 1994-03-11
-
公开(公告)号： US5447913A公开(公告)日： 1995-09-05
- 发明人: William S. Ammons , Roger G. Little
- 申请人： William S. Ammons , Roger G. Little
- 申请人地址： CA Berkeley
- 专利权人： Xoma Corporation
- 当前专利权人： Xoma Corporation
- 当前专利权人地址： CA Berkeley
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; A61P29/00 ; A61P31/04 ; A61P35/00 ; C07K14/435 ; C07K14/47 ; C07K19/00 ; C12P21/00 ; C07K14/52 ; A61K38/16
摘要：
Improved therapeutic uses of bactericidal/permeability-increasing protein (BPI) involve use of BPI protein product formulations in the form of physiologically stable dimeric associations of BPI protein product monomers characterized by enhanced in vivo biological activity. Preferred formulations include 50 percent or more by weight dimeric product.