发明授权
US5468846A Monoclonal antibodies and method for the determination of human G-CSF
失效
用于测定人G-CSF的单克隆抗体和方法
- 专利标题: Monoclonal antibodies and method for the determination of human G-CSF
- 专利标题(中): 用于测定人G-CSF的单克隆抗体和方法
-
申请号: US199493申请日: 1994-02-22
-
公开(公告)号: US5468846A公开(公告)日: 1995-11-21
- 发明人: Takanori Ichikawa , Tomoaki Kuwaki , Shigeru Matsuki , Katsumi Tachibana
- 申请人: Takanori Ichikawa , Tomoaki Kuwaki , Shigeru Matsuki , Katsumi Tachibana
- 申请人地址: DE Wilmington
- 专利权人: Kirin-Amgen Inc.
- 当前专利权人: Kirin-Amgen Inc.
- 当前专利权人地址: DE Wilmington
- 优先权: JPX5-162268 19930630
- 主分类号: C12P21/08
- IPC分类号: C12P21/08 ; C07K16/24 ; C12R1/91 ; G01N33/53 ; G01N33/577 ; G01N33/68 ; A61K35/14 ; C12N5/20
摘要:
The present invention relates to a high affinity monoclonal antibody and to an enzyme immunoassay of human G-CSF using the antibody.The trace amount of human G-CSF in samples such as body fluids from patients with hematological disorders can be measured without interference in the body fluids. For example, the measurable human G-CSF concentration in plasma is 0.5 pg/ml in minimum.