- 专利标题： Separation of enantiomers of non-steroidal anti-inflammatory drugs and chiral selector therefor
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申请号： US321200申请日： 1994-10-11
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公开(公告)号： US5484530A公开(公告)日： 1996-01-16
- 发明人: William H. Pirkle , Christopher J. Welch , Bo R. Lamm
- 申请人： William H. Pirkle , Christopher J. Welch , Bo R. Lamm
- 申请人地址： AZ Tucson
- 专利权人： Research Corporation Technologies, Inc.
- 当前专利权人： Research Corporation Technologies, Inc.
- 当前专利权人地址： AZ Tucson
- 主分类号： C07B57/00
- IPC分类号： C07B57/00 ; C07C51/487 ; C07C233/65 ; C07D307/00 ; C07D307/92 ; B01D15/08
摘要：
The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsterodial anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
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