发明授权
US5502057A Polysubstituted pyridines useful for treating lipoproteinanaemia and
arteriosclerosis
失效
可用于治疗脂蛋白血症和动脉硬化的多取代吡啶
- 专利标题: Polysubstituted pyridines useful for treating lipoproteinanaemia and arteriosclerosis
- 专利标题(中): 可用于治疗脂蛋白血症和动脉硬化的多取代吡啶
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申请号: US92655申请日: 1993-07-14
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公开(公告)号: US5502057A公开(公告)日: 1996-03-26
- 发明人: Rolf Angerbauer , Peter Fey , Walter Hu/ bsch , Thomas Philipps , Hilmar Bischoff , Dieter Petzinna , Delf Schmidt , Gu/ nter Thomas
- 申请人: Rolf Angerbauer , Peter Fey , Walter Hu/ bsch , Thomas Philipps , Hilmar Bischoff , Dieter Petzinna , Delf Schmidt , Gu/ nter Thomas
- 申请人地址: DEX Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DEX Leverkusen
- 优先权: DEX3801440.8 19880120; ITX21587/A88 19880729
- 主分类号: C07D213/55
- IPC分类号: C07D213/55 ; C07D405/04 ; C07D409/04 ; A61K31/44 ; C07D213/30 ; C07D213/57
摘要:
For the treatment of lipoproteinaemia and arteriosclerosis, the new disubstituted pyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl or heteroaryl,R.sup.2 is cycloalkyl or optionally substituted alkyl,R.sup.3 is hydrogen, cycloalkyl, or optionally substituted alkyl, aryl or heteroaryl,x is --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--,A is ##STR2## R.sup.6 is hydrogen or alkyl, and R.sup.7 is hydrogen, alkyl, aralkyl or a cation.
公开/授权文献
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