- 专利标题: Process for producing nucleosides
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申请号: US319574申请日: 1994-10-07
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公开(公告)号: US5506122A公开(公告)日: 1996-04-09
- 发明人: Hiroshi Yamauchi , Hideki Utsugi , Yuichiro Midorikawa
- 申请人: Hiroshi Yamauchi , Hideki Utsugi , Yuichiro Midorikawa
- 申请人地址: JPX Chiba
- 专利权人: Yamasa Shoyu Kabushiki Kaisha
- 当前专利权人: Yamasa Shoyu Kabushiki Kaisha
- 当前专利权人地址: JPX Chiba
- 优先权: JPX1-48785 19890228; JPX1-203556 19890804
- 主分类号: C12N1/20
- IPC分类号: C12N1/20 ; C12N9/12 ; C12P19/38
摘要:
The present invention concerns a process for producing nucleosides by carrying out the reaction of a base donor, a saccharide residue donor and a phosphoric acid donor by the use of an enzyme preparation containing nucleoside phosphorylase, thereby forming an N-glycosidic bond between the base moiety of the base donor and the saccharide moiety of the saccharide residue donor, which comprises using, as the enzyme preparation containing nucleoside phosphorylase, a preparation derived from the cells of one or more kinds of microorganisms belonging to thermophiles of the genus Bacillus and having high nucleoside phosphorylase activity per unit cell weight.