发明授权
US5521085A Transformed cell lines producing human monoclonal antibodies specific
for Pseudomonas aeruginosa serotypes
失效
产生对铜绿假单胞菌血清型特异性的人单克隆抗体的转化细胞系
- 专利标题： Transformed cell lines producing human monoclonal antibodies specific for Pseudomonas aeruginosa serotypes
- 专利标题（中）： 产生对铜绿假单胞菌血清型特异性的人单克隆抗体的转化细胞系
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申请号： US41244申请日： 1993-04-01
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公开(公告)号： US5521085A公开(公告)日： 1996-05-28
- 发明人: Tamotsu Fukuda , Yasushi Ono , Shiro Shigeta , Yasuyuki Kuriowa , Hisayoshi Ooka
- 申请人： Tamotsu Fukuda , Yasushi Ono , Shiro Shigeta , Yasuyuki Kuriowa , Hisayoshi Ooka
- 申请人地址： JPX Tokyo
- 专利权人： Mitsui Toatsu Chemicals, Inc.
- 当前专利权人： Mitsui Toatsu Chemicals, Inc.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX61-296594 19861215; WOXPCT/JP87/00976 19871214; JPX63-281460 19881109; JPX63-281461 19881109; JPX1-66326 19890320; JPX1-66327 19890320; JPX1-66328 19890320; JPX1-66329 19890320; JPX1-116048 19890511; WOXPCT/JP90/00367 19900319
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K16/12 ; C12N5/16 ; C12N5/10 ; C07K16/18
摘要：
The present invention relates to human monoclonal antibodies capable of plurally binding with O-antigens of Pseudomonas aeruginosa, relates to novel parent cell lines for producing human hybridomas derived from human immunoglobulin synthesizing cells, which cell lines themselves incapable of producing human immunoglobulin and capable of fusing with human antibody-producing cells, relates to human-human hybridomas which can secrete monoclonal antibodies capable of binding with at least one of serotypes of Pseudomonas aeruginosa, relates to pharmaceutical compositions for prophylaxis or therapy of Pseudomonas aeruginosa infectious diseases, and relates to prophylactic or therapeutic methods for Pseudomonas aeruginosa infectious diseases.
公开/授权文献
- US6118879A BTSC encoder 公开/授权日：2000-09-12
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