Invention Grant
- Patent Title: Polymer for making poly(ethylene glycol)-protein conjugates
- Patent Title (中): 制备聚(乙二醇) - 蛋白共轭物的聚合物
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Application No.: US456450Application Date: 1995-06-01
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Publication No.: US5539063APublication Date: 1996-07-23
- Inventor: John Hakimi , Patricia Kilian , Perry Rosen
- Applicant: John Hakimi , Patricia Kilian , Perry Rosen
- Applicant Address: NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: NJ Nutley
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K20060101 ; A61K31/745 ; A61K38/16 ; A61K38/19 ; A61K38/20 ; A61K38/21 ; A61K39/00 ; A61K39/38 ; A61K39/385 ; A61K47/42 ; A61K47/48 ; A61P37/00 ; A61P37/02 ; A61P43/00 ; C07C267/00 ; C07C331/18 ; C07C331/20 ; C07D211/04 ; C07D213/63 ; C07D213/64 ; C07D213/643 ; C07D213/70 ; C07D213/83 ; C07D213/89 ; C07K20060101 ; C07K1/00 ; C07K14/47 ; C07K14/52 ; C07K14/54 ; C07K14/545 ; C07K14/55 ; C07K14/555 ; C07K14/56 ; C07K14/765 ; C07K17/00 ; C07K17/02 ; C07K17/06 ; C07K17/08 ; C07K17/10 ; C08F116/02 ; C08F216/00 ; C08G65/02 ; C08G65/08 ; C08G65/26 ; C08G65/28 ; C08G65/32 ; C08G65/34 ; C08G65/48 ; C08H1/00 ; C08L23/36 ; C08L71/02 ; C12N9/96
Abstract:
The present invention is a polymer which may be used to produce a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein which forms this conjugate.
Public/Granted literature
- US5042897A Optical waveguide embedded light redirecting Bragg grating arrangement Public/Granted day:1991-08-27
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