发明授权
US5545652A Triazole and imidazole compounds and their use as antifungal therapeutic
agents
失效
三唑和咪唑化合物及其作为抗真菌剂的用途
- 专利标题: Triazole and imidazole compounds and their use as antifungal therapeutic agents
- 专利标题(中): 三唑和咪唑化合物及其作为抗真菌剂的用途
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申请号: US310995申请日: 1994-09-23
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公开(公告)号: US5545652A公开(公告)日: 1996-08-13
- 发明人: Katsumi Itoh , Kenji Okonogi , Akihiro Tasaka
- 申请人: Katsumi Itoh , Kenji Okonogi , Akihiro Tasaka
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX5-238340 19930924; JPX6-190766 19940812
- 主分类号: C07D233/58
- IPC分类号: C07D233/58 ; A61K31/4196 ; A61P31/10 ; C07D249/08 ; C07D521/00 ; A61K31/41 ; A61K31/415 ; C07D403/10
摘要:
The present invention provides an azole compound represented by the formula (I): ##STR1## wherein Ar is an optionally-substituted phenyl group; R.sup.1 and R.sup.2 are, the same or different, a hydrogen atom or a lower alkyl group, or R.sup.1 and R.sup.2 may combine together to form a lower alkylene group; R.sup.3 is a hydrogen atom or an acyl group; Y is a nitrogen atom or a methine group; and A is an optionally-substituted saturated cyclic amide group bonded through a first nitrogen atom, or a salt thereof, which is useful for prevention and therapy of fungal infections of mammals as antifungal agent.
公开/授权文献
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