发明授权
- 专利标题: Heterobiaryl derivatives
- 专利标题(中): 异二醇衍生物
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申请号: US375084申请日: 1995-01-19
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公开(公告)号: US5563268A公开(公告)日: 1996-10-08
- 发明人: Guenter Linz , Helmut Pieper , Frank Himmelsbach , Volkhard Austel , Thomas Mueller , Johannes Weisenberger , Elke Seewaldt-Becker
- 申请人: Guenter Linz , Helmut Pieper , Frank Himmelsbach , Volkhard Austel , Thomas Mueller , Johannes Weisenberger , Elke Seewaldt-Becker
- 申请人地址: DEX Biberach an der Riss
- 专利权人: Dr. Karl Thomae GmbH
- 当前专利权人: Dr. Karl Thomae GmbH
- 当前专利权人地址: DEX Biberach an der Riss
- 优先权: DEX4134467.7 19911018
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/4402 ; A61K31/4406 ; A61K31/4409 ; A61K31/4418 ; A61K31/4425 ; A61K31/4427 ; A61K31/445 ; A61K31/495 ; A61K31/50 ; A61K31/505 ; A61P7/02 ; A61P29/00 ; A61P35/00 ; C07D213/75 ; C07D213/81 ; C07D237/14 ; C07D237/20 ; C07D237/24 ; C07D239/28 ; C07D239/34 ; C07D239/36 ; C07D241/20 ; C07D401/06 ; C07D401/12 ; C07D417/12 ; C07F9/40 ; C07F9/6509 ; C07D403/02
摘要:
Heterobiaryl derivatives of the formulaR.sub.1 NH--X.sub.1 --X.sub.2 --X.sub.3 --Y.sub.1 --Y.sub.2 --Y.sub.3 --Y.sub.4 --E (I)whereinR.sub.1, X.sub.1 to X.sub.3 and Y.sub.1 to Y.sub.4 are as defined herein, the tautomers, stereoisomers and mixtures thereof, and the salts, particularly the physiologically acceptable salts, thereof with organic or inorganic acids or bases. The derivatives have valuable pharmacological properties, such as inhibiting cell-cell aggregation and cell-matrix interactions.
公开/授权文献
- US4968209A Automated material handling system for a cargo trailer 公开/授权日:1990-11-06