- 专利标题: Hepatitis C virus protease
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申请号: US350884申请日: 1994-12-06
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公开(公告)号: US5585258A公开(公告)日: 1996-12-17
- 发明人: Michael Houghton , Qui-Lim Choo , George Kuo
- 申请人: Michael Houghton , Qui-Lim Choo , George Kuo
- 专利权人: Chiron Corporation
- 当前专利权人: Chiron Corporation
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; C07K14/00 ; C07K14/18 ; C12N9/02 ; C12N9/50 ; C12N9/90 ; C12N15/57 ; C12Q1/18 ; C12Q1/37 ; C12R1/93 ; C12N15/40 ; C12N15/62
摘要:
The protease necessary for polyprotein processing in Hepatitis C virus is identified, cloned, and expressed. Proteases, truncated protease, and altered proteases are disclosed which are useful for cleavage of specific polypeptides, and for assay and design of antiviral agents specific for HCV.
公开/授权文献
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