发明授权
US5587319A Process for the preparation of L-phosphinothricin using transaminases of
different specificities in a linked process
失效
在连锁过程中使用不同特异性的转氨酶制备L-膦丝菌素的方法
- 专利标题: Process for the preparation of L-phosphinothricin using transaminases of different specificities in a linked process
- 专利标题(中): 在连锁过程中使用不同特异性的转氨酶制备L-膦丝菌素的方法
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申请号: US272286申请日: 1994-07-08
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公开(公告)号: US5587319A公开(公告)日: 1996-12-24
- 发明人: Johann Then , Werner Aretz , Klaus Sauber
- 申请人: Johann Then , Werner Aretz , Klaus Sauber
- 申请人地址: DEX Frankfurt am Main
- 专利权人: Hoechst Aktiengesellschaft
- 当前专利权人: Hoechst Aktiengesellschaft
- 当前专利权人地址: DEX Frankfurt am Main
- 优先权: DEX3842025.2 19881214
- 主分类号: C12P13/04
- IPC分类号: C12P13/04 ; C12P41/00 ; C12R1/10 ; C12R1/19 ; C12P19/02
摘要:
L-2-Amino-4-methylphosphinobutyric acid can be prepared by a racemate resolution in the presence of D-aminoacid and L-aminoacid transaminases by reaction with .alpha.-keto acids and amino-group donors. In particular, transaminases from Bacillus licheniformis and from Escherichia coli are used.
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