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US5599907A Production and use of multimeric hemoglobins 失效
多聚体血红蛋白的生产和使用

Production and use of multimeric hemoglobins
摘要:
Multimeric hemoglobin-like proteins are obtained by crosslinking cysteines of the component tetramers, or by genetically fusing globin-like domains of one tetramer with those of another, by means of an interdomain spacer sequence. Artificial cysteines are introduced selectively in a single globin-like domain per tetramer to control polymerization.
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